The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs). Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins. In mammals. there are four AGO proteins (AGO1-4). https://tonerparts.shop/product-category/mailbox-bin/